Leica microscope

CIKA is committed to providing funding for research into solid tumours

Leica microscope - Cancer in Kids @ RCH - CIKA

Leica M165FA fluorescence microscope

Solid tumours arise from the abnormal growth and distribution of cells that appear very similar to normal cells within the same tissue. One of the very significant challenges in solid tumour research is being able to identify which cells are going to form a tumour before they have grown enough to become dangerous. Researchers have identified a range of proteins that are produced by the tumour cells but not by the normal cells. These proteins cannot be seen with the naked eye but can be seen using special microscope-based techniques that use very precise wavelengths of light. This technique, known as fluorescence microscopy, allows researchers to peer into the tissue to see the growing tumour cells and understand more about how they interact with each other and the surrounding normal tissue.

This specialized technique requires state of the art microscopes and dedicated software. The Leica M165FA fluorescence microscope is fully automated allowing a very high degree of accuracy when imaging whole tumours and tumour derived cells. The software that controls the microscope allows live cells to be viewed in real time as they interact with each other and these interactions can be filmed to allow researchers to examine the abnormal behaviour of tumour cells in very great detail.

This technology allows researchers to see tumours in ways not previously possible and directly contributes to understanding how to stop tumours growing before they can do harm.

Footnote, November 2013.
The microscope was purchased in May 2013 and immediately put to use to examine the morpholgy of cells derived from tumour biopsies. Click here to read the report from the people who have been using it.