TRAIL

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TRAIL - Cancer in Kids @ RCH - CIKA

The TRAIL programme was carried out in the Apoptosis Laboratory at the RCH. Its purpose was to develop a new technique to predict the responses of solid tumour patients to conventional and novel anti-cancer drugs. Novel agents to be tested included "TRAIL" (TNF-related apoptosis inducing ligand).

Expected Outcomes:
Establish whether TRAIL will be effective in treating solid tumours by developing a new technique and analysing fifty tumours during 2005. The new technique will enable tailored treatment protocols which should reduce later-life side effects from cancer treatment

CIKA Funding Commencement:
2005

Expected Completion:
2006

Milestone:
NHMRC Funding in 2007. Development of mouse models.

Cancers targetted:
Neuroblastoma, Wilms' tumour, Ewing's sarcoma, osteosarcoma.

Further details of this project were reported in the first CIKA Newsletter for 2007 and can be found by clicking here.